The Rose Project Research Team

Peter K. Gregersen, MD, Principal InvestigatorPeter K. Gregersen, MDPrincipal Investigator
Dr. Gregersen is Head of the Robert S. Boas Center for Genomics and Human Genetics and Professor, Molecular Medicine and Medicine at Hofstra North Shore-LIJ School of Medicine. He obtained his MD degree from Columbia University College of Physicians and Surgeons in 1976, followed by fellowship training in rheumatology at the Hospital for Joint Diseases/NYU. Dr. Gregersen’ career has focused on the genetics of autoimmune disorders, but has recently expanded to include investigation of the genetics and biology of endometriosis.

During the 1980’s Dr. Gregersen cloned and sequenced the major HLA class II alleles associated with rheumatoid arthritis and first described the “shared epitope” hypothesis to explain the complex pattern of HLA associations with rheumatoid arthritis. Since this critical discovery, Dr. Gregersen has worked in the area of genetics and led several major international consortia to study the genetics of rheumatoid arthritis, systemic lupus, myasthenia gravis, myositis and other autoimmune disorders. He founded the North American Rheumatoid Arthritis Consortium (NARAC) which has made major contributions to identifying risk alleles associated with rheumatoid arthritis.

Dr. Gregersen has spearheaded the development of a robotic biorepository and informatics resources to support these studies, including a large normal control registry (gapregistry.org) with a view toward understanding genotype-phenotype relationships in both normal and disease populations. He also has longstanding interests related to the genetics of absolute pitch and synesthesia, as well as studies of immunological aspects of autism. Endometriosis is a new line of research for Dr. Gregersen’s laboratory, but it is a natural extension of his interest in better understanding basic disease mechanisms involved in immunity and inflammation.

In May 2013, the Royal Swedish Academy of Sciences awarded Dr. Gregersen the Crafoord prize for his genetic research in rheumatoid arthritis.   He has also been honored with the 2007 Klemperer Medal from the New York Academy of Medicine, the 2007 ACR Distinguished Basic Investigator Award, and elected to the Association of American Physicians in 2009.

 

Christine Metz, PhDChristine Metz, PhD
Dr. Metz, is an investigator at the Feinstein Institute for Medical Research and Professor at the Hofstra-North Shore-LIJ School of Medicine. In addition, she is the Director of Research for the Department of OB-GYN at North Shore University Hospital and Long Island Jewish Medical Center of the Hofstra-North Shore-LIJ School of Medicine.

Dr. Metz graduated from Cornell University with BS and MS degrees and she completed her PhD in Immunology/Pathology at New York University. She began her scientific career studying the role of macrophage migration inhibitory factor (or MIF) in numerous inflammatory conditions. In 2001, Dr. Metz established her laboratory at the North Shore-LIJ Research Institute (re-named The Feinstein Institute for Medical Research in 2008).

Dr. Metz’s research focuses on inflammation, a complex biological response to infection and injury, in both pregnant and non-pregnant populations. Throughout her career, she has studied numerous conditions that affect women including, rheumatoid arthritis, endometriosis, cardiovascular disease, preeclampsia, and preterm labor. Her work identifying ways to reduce and prevent dysfunctional inflammation has been funded by the American Heart Association, the National Institutes of Health and the NY State Dept of Public Health. Dr. Metz has published over 110 peer-reviewed research papers and book chapters, and has been an inventor or co-inventor on five patents.

 

Tamer Seckin, MDTamer Seckin, MD
Dr. Seckin is a Board Certified gynecologist and laparoscopic surgeon in private practice in New York City, practicing at Lenox Hill Hospital of the North Shore – LIJ Health System.   He specializes in treating women with endometriosis. He is an internationally known specialist in minimally invasive advanced (laparoscopic) surgery, and is among a very limited number of gynecologic surgeons in the United States who is exclusively committed to the deep laparoscopic excision of endometriosis.

Dr. Seckin completed his gynecological training at the Children’s Hospital, State University of New York, Buffalo, in 1985. In the early 90’s, his interest in minimally invasive surgery became a passion as he became acquainted with the world renowned laparoscopic pioneer, Dr. Harry Reich.   Together with Reich, he established in 1995 a private practice group for the treatment of endometriosis; Advanced Laparoscopic Surgeons of New York.

In 2009, Dr. Seckin founded the Endometriosis Foundation of America (EFA), the first research and advocacy foundation of its kind organized by a private physician to raise awareness and emphasize the critical value of surgical excision of endometriosis. Under his guidance as Medical Director, the EFA strives to increase disease recognition, provide advocacy, facilitate expert surgical training, and fund landmark endometriosis research.

In 2010, Dr. Seckin organized the first EFA Annual Medical Symposium. Each year this medical conference brings the top surgeons and scientists from around the world together to speak and train the next generation of medical professionals. This same year, Dr. Seckin founded the Fellowship in Minimally Invasive Gynecologic Surgery (FMIGS) in affiliation with the AAGL/SRS at North Shore/LIJ-Lenox Hill Hospital, where he is also the Clinical Instructor for Obstetrics & Gynecology. He has written book chapters and articles on both subjects and he is currently a contributing editor for Gynecological Surgery.

Dr. Seckin is the treasurer and an executive committee member of the International Society of Gynecological Endoscopy (ISGE). He is also a member of the American Medical Association, the American College of Obstetrics and Gynecology, the European Society of Reproductive Endocrinology, the Society of Laparoscopic Surgeons, The American Association of Gynecologic Laparoscopy, The American Fertility Society, The American Society for Reproductive Medicine, The Society of Reproductive Surgeons, The New York Gynecological Society and The Society of Reproductive Endocrinology and Infertility.

Maya Tevlin, PhDMaya Tevlin, PhD
Before joining the Center of Genomics and Human Genetics, to work on the ROSE study, Dr. Tevlin was a Researcher in the Laboratory of Developmental Genetics at the Rockefeller University. She received her PhD in Genetics and Immunology at the Hebrew University, Jerusalem, Israel in 2004, and her Postdoctoral Degree at the Rockefeller University in 2009. Dr. Tevlin is a recipient of several scientific fellowships and awards, including The Druckenmiller Fellowship from the New York Stem Cell Foundation. Her work has been published in the leading scientific journals such as Science, Nature and Nature Immunology.

 

Mary Keogh, RN, MSN, ANPMary Keogh, RN, MSN, ANP
Mary is the manager of the Feinstein Institute’s Tissue Donation Program, which oversees the ROSE study. She began her career as a critical care nurse. Over the past 15 years she has held several nursing roles in medical research, and joined the North Shore -LIJ Health System in 2005 to manage the TDP. She has an undergraduate degree in Nursing from Binghamton University and a Masters in Nursing from Columbia University.

 

Margaret DeFranco, RN

Margaret DeFranco, RN
Margaret received her BS in Biology from the Rochester Institute of Technology and worked in cell research at the start of her career. She went on to receive her BS in Nursing from CUNY-Lehman College in 1986. Margaret worked in varied nursing positions in the North Shore-LIJ Health System, including telemetry and anesthesia pain management, before joining the ROSE study as a Research Nurse Coordinator.

 

Michael-Ryan-research-teamMichael Ryan
Michael is the Manager of the Biorepository at The Feinstein Institute for Medical Research. He is responsible for the thousands of samples that are being managed and maintained within the Biorepository. His role includes developing and maintaining the sample processing protocols and the Biorepository SOPs. With more than 10 years of experience, Michael is highly skilled at biological sample processing and management for research. He has aided investigators process, track, store and distribute various samples for over 50 different research studies. He also helps investigators choose the best collection and storage methods for their projects. Michael is HIPPA and CITY trained and certified.   He is dedicated to making sure that all samples are handled properly and safely to ensure good quality research specimens.

 

Brandon Blau, Research AssistantBrandon Blau, Research Assistant
Brandon received his A.B. in Chemistry from Princeton University in 2014 and is working on the ROSE study as a Research Assistant. Brandon is a familiar face in the lab, having spent several summers since high school studying the genetic basis of systemic lupus erythematosus. Brandon’s role within the ROSE study involves investigating whether menstrual flow at the cellular level differs between women with endometriosis and unaffected women.

 

Anna YeoAnna Yeo
Anna recently received her Bachelor of Science in Biology from Union College and joined the ROSE study as an Assistant Research Coordinator after graduation.

 

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Patient Reviews

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  • Angela Aro

    I have struggled with endometriosis and adenomyosis since first starting my period at 13. I was diagnosed at 21 and what followed was a series of unsuccessful surgeries and treatments. My case was very aggressive and involved my urinary tract system and my intestines. After exhausting all of my local doctors I was lucky enough to find Dr. Seckin. We…

  • Emi O

    Seckin and Dr. Goldstein changed my life!

  • Kristin Sands

    Like so many women who have tirelessly sought a correct diagnosis and proper, thorough medical treatment for endometriosis, I found myself 26 years into this unwanted journey without clear answers or help from four previous gynecological doctors and two emergency laparoscopic surgeries. I desperately wanted to avoid the ER again; a CT scan for appendicitis also revealed a likely endometrioma…

  • Wilfredo Reyes

    Dr. Seckin literally gave my wife her life back. I am eternally grateful to him for his generous, determined spirit to see that Melanie finally live free from the prison bonds of Endometriosis.

  • Carla

    I am so grateful to Dr Seckin and Dr. Goldstein. My experience was nothing short of amazing. I was misdiagnosed with the location of my fibroids and have had a history of endometriosis. Dr. Seckin was the one who accurately diagnosed me. Dr Seckin and Dr. Goldstein really care about their patients and it shows. They listened to my concerns,…

  • Melissa Boudreau

    When I think of Dr. Seckin these are the words that come to mind. Gratitude, grateful, life-changing, a heart of gold. I feel compelled to give you a bit of background so you can understand the significance of this surgery for me. I am passionate about Endometriosis because it has affected me most of my life and I have a…

  • Jaclyn Harte

    Dr. Seckin and Dr. Goldstein radically changed my quality of life. They treat their patients with dignity & respect that I've personally never seen in the literally 25+ doctors I've seen for endometriosis. This summer, I had a surgery with Dr. Seckin & Goldstein. It was my first with them, but my 5th endo surgery. I couldn't believe the difference,…

  • Megan Rafael Moreno

    I was in pain for 2 years. I was getting no answers, and because dr Goldstein and dr seckins were willing to see and treat me I'm finally feeling almost back to normal. They were very down to earth and helpful in my time of need. Dr Goldstein was easy to talk to and caring, she took care of me…

  • Nancy Costa

    Dr. Seckin is one of the best endometriosis surgeon. Every time I go to the office, he really listens to me and is always concerned about my issues. Dr Seckin's office staff are a delight and they always work with me. I feel I can leave everything to them and they will take care of it. Thank you to the…

  • Rebecca Black

    Fast forward 5 years to find out incidentally I had a failing kidney. My left kidney was only functioning at 18%. During this time, I was preparing all my documents to send to Dr. Seckin to review. However, with this new information I put everything on hold and went to a urologist. After a few months, no one could figure…

  • Monique Roberts

    I'll never stop praising Dr. Seckin and his team. He literally gave me back my life.

  • Erin Brehm

    I had a wonderful experience working with Dr. Seckin and his team before, during and after my surgery. I came to Dr. Seckin having already had laparoscopic surgery for endometriosis 5 years prior, with a different surgeon. My symptoms and pain had returned, making my life truly challenging and my menstrual cycle unbearable. Dr. Seckin was quick to validate my…

  • Anita Schillhorn

    I came to Dr. Seckin after years of dealing with endometriosis and doctors who didn't fully understand the disease. He quickly ascertained what needed to be done, laid out the options along with his recommendation and gave me the time to make the right decision for me. My surgery went without a hitch and I'm healing very well. He and…

  • Nicholette Sadé

    Dr. Seckin brought me back to life! I am now 3 weeks into my recovery after my laparoscopy surgery, and I feel like a new and improved woman! Being diagnosed with Endometriosis, then 25yrs old in 2015, and discovering the severity of my case being stage 4, made me devastated. Dr. Seckin's vast knowledge of the disease, sincere empathy, and…